Research Associate

Applications are invited for a postdoctoral research associate in the National Heart & Lung Institute, Imperial College London. The 36-month post is funded by the Medical Research Council to investigate advanced therapeutic approaches for tissue repair and in collaboration with AstraZeneca. You will be based within the Inflammation, Repair and Development section where you will be part of the multidisciplinary research team led by Dr Asha Patel.

Aberrant repair after acute or chronic injury of major organs such as the lung can lead to fibrosis, irreversible scarring and loss of function. This project will investigate if manipulation of gene expression can guide epithelial regeneration in vivo and in vitro using organoid or air liquid interface models.

We are looking for an ambitious and motivated postdoc with a background in developmental biology/regenerative medicine/pharmacology to develop RNA tools to manipulate pathways implicated in tissue regeneration that may be harnessed for wound healing.

Duties and responsibilities

• The successful applicant will be responsible for management of projects developing RNA based tools to modulate repair, with a focus on lung injury.

• Identify and develop methods for the collection and analysis of data.

• Undertake training to acquire expertise to carry out the project.

• Actively participate in the research programme of the lab, work collaboratively, and supervise academic trainees.

• You will be encouraged to present at national and international scientific meetings, publish in high quality journals, attract funding, and develop your career.

Essential requirements

• PhD in regenerative medicine, pharmacology, developmental biology, bioengineering, life sciences or another relevant field.

• Practical experience in mammalian cell culture and/or in vivo training.

• Some experience in microscopy, image analysis, flow cytometry, molecular biology techniques (e.g., ELISA) and/or histology.

• Research experience and knowledge of research methods and statistical analysis.

• Knowledge of wound healing/ repair, stem cell or developmental biology.

• Strong analytical, organisational and problem-solving skills.

• Exceptional communication skills.

• Ability to work within a diverse team.

Further information

Full details are available in the on-line job description and prospective candidates should complete the on-line application process.

Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £38,194 - £41,388 per annum.

Should you require any further details on the role please contact: asha.patel@imperial.ac.uk

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see: https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level.http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research/

Documents

• Research Associate JD MED03851.pdf